Live extension. Longevity
Healthy lifestyle

As dogs age, many develop more than one chronic health condition. New research from the Texas A&M College of Veterinary Medicine and Biomedical Sciences (VMBS) shows those conditions can dramatically shorten a dog's lifespan, highlighting the importance of managing multiple diseases together rather than individually.

NOAA puts a very strong El Niño above 90% for winter 2026-27, with a 69% chance of a record event. Here is what that means for household health.

Aging clocks can be readily produced by using what are by now well established machine learning techniques on any body of biological data that changes with age. Omics data is favored, as there are a great many databases of such data for large study populations, but clocks have been made using clinical chemistry results from simple blood tests, imaging data, and many other items. A clock is calibrated to predict age in the reference population, and when used on people outside that reference populations, most clocks tend to predict a higher age for people more greatly impacted by aging. Thus a higher clock age than chronological age tends to correlate with increased mortality risk, presence of age-related conditions, and so forth, at least over populations. […]

The Mediterranean diet is simpler and less expensive than you think.

A simple waist measurement may be nearly as effective as more complicated methods for detecting unhealthy levels of body fat. Researchers also found that BMI alone missed many people with obesity, suggesting waist size could provide an important warning sign.

Northwest Naturals recalled two frozen raw pet foods for Salmonella and Listeria. The FDA warns that people can get sick from handling them.

BINGHAMTON, N.Y. — The Northeast Organic Farming Association of New York (NOFA-NY) is celebrating Organic Month this September with the launch of “Give to Grow Organic,” a month-long campaign encouraging New Yorkers to support organic farmers and the local food system in simple, meaningful ways. From choosing organic products at the grocery store to visiting […] The post NOFA-NY Launches "Give to Grow Organic" Campaign to Celebrate Organic Month appeared first on Morning Ag Clips.

One might think that an alteration to the machinery of gene expression that systemically changes the amino acid components of proteins, in effect giving all proteins the possibility of multiple single nucleotide polymorphisms, would be quite harmful. But some forms of mistranslation of RNA into protein actually extend life span, as demonstrated in flies. The reason why this happens is unknown at the present time. It is suspected that this is a hormetic effect of some sort, mistranslation triggering stress responses that clean up the cell for an overall benefit. The evidence presented here argues against a meaningful role for stress and stress response in mistranslation induced longevity, however. Accurate translation of genes into proteins is critical to organism fitness, and errors in this process […]

Why do women live longer than men? An evolutionary question sparks a new hypothesis that dovetails with a growing movement in longevity research.

A drug that millions of people with breast cancer already take every day may be hiding a second, unexpected talent: the ability to silence the inflammatory uproar of aged and damaged cells that accumulate in our tissues and quietly poison them from within. In a new study published in Nature Aging, researchers report that short-term […]

The intestines rely on different strategies to rebuild themselves in response to diet changes versus infections, according to a new Cornell study—a finding that can shed light on how gut health adapts to harsh conditions, flourishing ecosystems of microbes and variable diets.

A magnetotactic bacterium extended lifespan in worms by 43.39% and appeared to do so by suppressing ferroptosis. A bacterium best known for producing microscopic magnetic structures may have an unexpected effect on aging. In experiments with Caenorhabditis elegans, the magnetotactic bacterium Magnetospirillum magneticum AMB-1 extended average lifespan by 43.39% while helping preserve neurological function and [...]

The secret to a long life may lie in the genomes of the longest-lived mammals for their size: bats. That idea captivated Juan Manuel Vazquez when he was a graduate student at the University of Chicago, but at the time he couldn't find any good published information on bat genomes to provide clues. Once he became a UC Berkeley postdoctoral fellow in 2020, however, he unleashed his passion and began scouring the Western U.S. for bat species that could provide tissue samples and DNA to sequence.

Imagine hospitals scattered across a country jointly teaching a single artificial intelligence to spot hidden health-risk patterns — without a single weight measurement, meal log, or exercise record ever leaving the building where it was collected. That is the promise behind a new study from researchers at Manipal Institute of Technology Bengaluru, part of Manipal […]

Hardened Ground: How Stiffening Tissue May Be Quietly Draining Human Fertility Aging has long been narrated as a story written in hormones, genes and mitochondria, but a new synthesis argues that some of the most consequential chapters may be written in something far more tangible: the physical stiffness of the tissue itself. In a review […]

Banished Decades Ago, Toxic PCBs May Still Be Eroding Children’s Brains — and Their Telomeres More than two decades after the world’s industrialized nations agreed to phase them out, polychlorinated biphenyls are still being measured in the blood of schoolchildren — and a sweeping new study suggests they may be leaving a molecular fingerprint on […]

Keto diet cut liver fat by 67% in a clinical trial  Science DailyObesity: Keto May Offer More Benefits Than Mediterranean Diet  HealthlineKeto diet has greater health benefits than other popular weight-loss diets, according to clinical trial  Medical XpressScientists Pitted Keto Against Mediterranean And Low-Fat Diets. Keto Won on One Clear Health Measure.  ScienceAlertLow-carb diet delivers added liver benefits beyond weight loss  WashU Medicine

Keto diet cut liver fat by 67% in a clinical trial  Science DailyObesity: Keto May Offer More Benefits Than Mediterranean Diet  HealthlineKeto diet has greater health benefits than other popular weight-loss diets, according to clinical trial  Medical XpressScientists Pitted Keto Against Mediterranean And Low-Fat Diets. Keto Won on One Clear Health Measure.  ScienceAlertLow-carb diet delivers added liver benefits beyond weight loss  WashU Medicine

Dogs and humans may have more in common when it comes to aging than scientists realized. Researchers with the Dog Aging Project found that patterns of small molecules in dogs’ blood were linked to longer or shorter lifespans in remarkably similar ways to those seen in people. These metabolic “fingerprints” could offer clues about the biological processes that drive aging, including metabolism, inflammation, and cellular stress.

Improved fitness did not prevent prolonged sitting from impairing blood-vessel function in the legs. Long hours of sitting are often treated as something a good workout can offset. But new research from Dalhousie University suggests the cardiovascular effects of prolonged inactivity may be harder to undo. Published in the European Journal of Applied Physiology, the [...]

A Ten-Percent Warning: A Simple Breathing Test May Predict Deadly Lung Disease Months Earlier in Children After Bone Marrow Transplants For the smallest recipients of life-saving bone marrow transplants, the gravest threats do not always announce themselves with fever or crisis; some arrive as a whisper. A new study from China reports that a subtle […]

​Traditional weight-loss strategies for children, from calorie restriction to general aerobic exercise, often carry an unwanted side effect: they cut fat, but they also erode muscle mass.

Cancer’s ability to evade the immune system may depend on a metabolic conversation between two very different immune-cell populations, according to a study published in Nature Cancer. Researchers report that regulatory T cells infiltrating tumors can use the nutrient-rich, chemically hostile environment around them to promote the decline of natural killer cells, weakening one of […]

A study spanning England and China has identified a statistically significant association between urinary incontinence and the later emergence of self-reported hearing loss in adults aged 50 and older. The finding, reported by researchers Hao Li, Meng Ge and Xiaowen Zhang, links two conditions that are often treated separately in clinical practice but commonly appear […]

In a tale of identities as divergent as "The Prince and the Pauper," a well-known cancer-causing gene also influences cells in a zombie-like state meant to prevent cancer.

“Shoppers are feeling less control of their spending on food and more concerned about food prices than in February 2026.” Researchers with The Food Industry Association discussed their latest research into U.S. consumers’ worries about food prices’ impacts on family meals this week, and their findings comport with what I see happening in peoples’ self-care choices at-home directly impacting nutrition as well as adjacent areas of retail health and home health life-flows. This data point meshes with trends in geopolitics, home economics, and consumers’ growing demand for self-care outside of traditional “front doors” compelling me to call-out the health risks accompanying the high and higher costs of food.         Start with geopolitics, which this week prompt me to focus on President Trump’s latest call for tariffs on Canada. Follow this announcement the IFPA immediately warned its stakeholders — the largest

This is today’s edition of The Download, our weekday newsletter that provides a daily dose of what’s going on in the world of technology. A startup claims it’s found a drug to make your blood young —Antonio Regalado I knew I’d officially become a “longevity influencer” when a company called Generation Lab offered me the…

Researchers here show that a few different senolytic approaches improve the state of the population of microglia in the white matter of the brain in aged mice. This is much as one might expect, given past work into the effects of clearing senescent cells on cognitive function and neurodegeneration in various mouse models. Microglia are innate immune cells of the brain. The presence of senescent and inflammatory microglia is important in the age-related disruption of normal function in the brain, and removing them is beneficial. Sadly, little progress has been made to date in assessing established low-cost senolytic drugs in patients with neurodegenerative conditions; one small clinical trial was conducted for Alzheimer's disease, and that is about it. Brain white matter undergoes structural and functional […]

Tiny Biological Couriers Could Turn the Body’s Anti-Aging Systems Back On A new review of extracellular vesicles (EVs) presents these naturally occurring nanoparticles as one of the most versatile platforms yet proposed for anti-aging medicine. Rather than attempting to block a single aging pathway, EV-based therapies could theoretically coordinate several of the biological processes that […]

Obesity: Keto May Offer More Benefits Than Mediterranean Diet  HealthlineScientists Pitted Keto Against Mediterranean And Low-Fat Diets. Keto Won on One Clear Health Measure.  ScienceAlertKeto diet has greater health benefits than other popular weight-loss diets, according to clinical trial  Medical XpressIs the keto diet better than the Mediterranean? New clinical trial reveals health benefits  Scientific AmericanA Study Found Keto, Mediterranean, and Plant-Forward Diets Cut Weight Equally. 1 Decreased Liver Fat by 67 Percent  inc.com

Obesity: Keto May Offer More Benefits Than Mediterranean Diet  HealthlineScientists Pitted Keto Against Mediterranean And Low-Fat Diets. Keto Won on One Clear Health Measure.  ScienceAlertKeto diet has greater health benefits than other popular weight-loss diets, according to clinical trial  Medical XpressIs the keto diet better than the Mediterranean? New clinical trial reveals health benefits  Scientific AmericanA Study Found Keto, Mediterranean, and Plant-Forward Diets Cut Weight Equally. 1 Decreased Liver Fat by 67 Percent  inc.com

If you have spent any time in longevity circles, you’ve probably heard the claim that sauna use can help you live longer. The idea is appealing because it seems refreshingly simple: Sit in a hot enclosure, sweat, relax, meditate, and maybe do something good for your future self at the same time.  The sauna longevity […] The post Sauna and Longevity: What the Science Shows first appeared on NOVOS.

A Study Found Keto, Mediterranean, and Plant-Forward Diets Cut Weight Equally. 1 Decreased Liver Fat by 67 Percent  inc.comIs the keto diet better than the Mediterranean? New clinical trial reveals health benefits  Scientific AmericanKeto diet has greater health benefits than other popular weight-loss diets, according to clinical trial  Medical XpressObesity: Keto May Offer More Benefits Than Mediterranean Diet  HealthlineScientists Put Three Weight-Loss Diets Head to Head. Only One Changed The Liver.  ScienceAlert

A Study Found Keto, Mediterranean, and Plant-Forward Diets Cut Weight Equally. 1 Decreased Liver Fat by 67 Percent  inc.comIs the keto diet better than the Mediterranean? New clinical trial reveals health benefits  Scientific AmericanKeto diet has greater health benefits than other popular weight-loss diets, according to clinical trial  Medical XpressObesity: Keto May Offer More Benefits Than Mediterranean Diet  HealthlineScientists Put Three Weight-Loss Diets Head to Head. Only One Changed The Liver.  ScienceAlert

Precancerous blood cells can actively reshape their surroundings, prematurely aging cells in the bone marrow to create conditions that favor their own growth and potentially increase the risk of blood cancer, according to a new study by researchers at The Jackson Laboratory (JAX).

Exercise does more than keep our minds and bodies healthy. It also protects us against the effects of aging. Scientists have developed self-contracting mini-muscle implants that grow their own blood supply and mimic the biological benefits of exercise, giving people unable to work out because of physical limitations a way to reap the same rewards.

Scientists Put Three Weight-Loss Diets Head to Head. Only One Changed The Liver.  ScienceAlertSee more headlines & perspectives on Google News

Scientists Put Three Weight-Loss Diets Head to Head. Only One Changed The Liver.  ScienceAlertSee more headlines & perspectives on Google News

Researchers at the Center for Regenerative Medicine (CReM) at Boston Medical Center (BMC) and Boston University (BU) have developed a scalable method for generating CD4+ helper T cells from induced pluripotent stem cells (iPSCs), overcoming a longstanding challenge in the development of stem cell-based immunotherapies.

A diet that severely limits carbohydrates but is high in fat has the greatest health benefits for people with obesity compared to a Mediterranean diet or a low-fat diet, according to a clinical trial publishing August 27 in the Cell Press journal Cell Metabolism.

In a clinical trial, people with obesity saw clear health benefits on the keto diet that they didn’t see on two other popular eating regimens

The Brain’s “Waste” Pigment May Reveal a Hidden Failure in Cellular Recycling For more than a century, scientists have recognized lipofuscin as one of the brain’s most persistent signs of aging: a yellow-brown, naturally fluorescent material that accumulates inside cells and becomes increasingly visible over time. Now, an international research team has traced this enigmatic […]

If sleep has become harder to come by after 50, exercise is… Content source - www.soundhealthandlastingwealth.com

Some people with epilepsy experience delusions, hallucinations, paranoia and confusion after a seizure.

A healthier diet is linked to better lung function among adults with asthma or COPD, with the largest gains seen among those with COPD.

Intrinsic capacity is quickly becoming a preferred way to measure and assess human aging.

Dual-task training and mind-body exercise are most beneficial for post-stroke depression in older adults; resistance training leads for post-stroke anxiety, a study shows.

Abstract: The Regenerative Paradox: Regenerative agriculture promises environmental benefits, but vague standards allow greenwashing to flourish. This guide helps you distinguish genuine sustainable farming practices from marketing claims by examining soil health, water stewardship, pest management, and energy use. Learn what to look for when verifying sustainability in potato farming and other crops. Regenerative agriculture […] This information The “Regenerative Paradox”: When Farming Claims Sustainability but Delivers Greenwashing  appeared first on AgriFarming

A fish fin can lose a substantial portion of its skeletal structure and still rebuild itself to remarkably precise proportions. A new study of zebrafish regeneration suggests that this apparent biological memory is encoded not in a single permanent blueprint, but in a dynamic chemical signal that measures how much tissue has been removed and […]

The adult human brain has limited capacity to repair or regenerate neurons lost to Alzheimer's disease, the most common type of dementia.

A small pilot study from Thailand suggests that adolescents who undergo hematopoietic stem cell transplantation may develop a strong and persistent antibody response after receiving two doses of the human papillomavirus vaccine, challenging the assumption that three doses are always necessary for this medically vulnerable group. The findings, published in BMC Infectious Diseases, offer early […]

A Nature Medicine analysis ran 16 epigenetic clocks across 51 longevity studies. Most interventions moved nothing, and senolytics disagreed.

Adults with at least one parent who reached age 100 lived longer and had substantially lower risks of cardiovascular disease and hypertension than people whose parents had shorter lifespans, according to a study published today in JAMA Network Open.

The immune system is very complex, and immune cells exist in a continuum of states rather than being separated into clearly demarcated pigeonholes of behavior. Many of the categorizations applied to immune cells, largely based on cell surface marker differences, are conceptually useful, but also greatly oversimplify a complex reality. Sometimes one has little need of the deeper details, and it is certainly true that modern medicine has come a long way on a very incomplete map of immune system details, but equally sometimes the deeper details are critical to understanding how the immune system behaves and can be manipulated for benefit in a given situation. Today's open access paper provides an example of one nice, neat category of immune cells fraying at the edges […]

Traffic noise disrupts recognised benefits of bird song and other sounds from nature, a new study from the University of Surrey reports.

Bats are anomalies in the mammalian world—they fly, have long lifespans and rarely get cancer. Scientists now suspect the bat immune system enables them to live longer without disease, according to a new study published today in Nature.

HEALTH survey suggests the longevity conversation is shifting from living longer toward living better and the industry may need to catch up. HEALTH’s new Longevity Insights Report, based on responses from 1,000 Americans, raises some uncomfortable questions for an industry racing toward the future: are biohackers building for an audience that doesn’t exist? While tech […] The post New survey reveals what Americans really want from longevity appeared first on Longevity.Technology.

WEDNESDAY, Aug. 26, 2026 — A short bout of exercise appears to work quicker than a long nap to refresh a sleep-deprived mind, a new study says.About 20 minutes of moderate-to-vigorous exercise performed as well as a 90-minute nap in protecting the...

Moderate calorie restriction lowered an immune protein called C3 that appears to help drive chronic inflammation as the body ages. Blocking the same protein reduced age related inflammation in mice, raising the possibility that future treatments could mimic some benefits of calorie restriction without severe dieting.

Director Baek Jong-yeol teamed up with actor Koo Kyo-hwan to adapt the popular webtoon "Reawakened Man" into the action film "Reawaken Man: The Red." The director said he focused on reshaping the original comic's premise into a fast-paced action film about an unemployed youth who gains the ability to revive after death. "The original webtoon has a very famous premise about an ordinary person acquiring a completely extraordinary power," Baek, a former commercial and music video director who previously directed "The Beauty Inside" (2015) and Netflix's "Believer 2" (2023), said Wednesday. "My main focus was figuring out how to effectively reconstruct this narrative within the short runtime of a film medium." "Reawaken Man: The Red" follows Seok-hwan (Koo), an unemployed young man. After dying, he realizes he possesses a supernatural ability to revive 72 hours after death, which makes him the target of a mysterious group. Koo continues his impressive box-office streak following his lead

This popular science article discusses recent research that categorizes age-related changes a few thousand different cell populations in the body, distinguished by transcriptional behavior. This big picture view of aging shows a wide variety of responses to aging between cell types that occur in a staged progression throughout life, which the researchers characterize as a grand remodeling of the society of cells. The principle scientist in question favors a programmed aging viewpoint, but as is always the case, whether one thinks aging is a program like development that is under evolutionary selection or instead an accumulation of damage that occurs because health and fitness in later life is not under strong evolutionary pressure, the actual observations can be made to fit any theory of aging. […]

Dolly Parton's life in her own words reveals her Smoky Mountains childhood, faith, marriage to Carl Dean and her views on aging and what comes after.

Self-contracting myografts improved muscle, bone and metabolic measures in aging mice – without requiring the animals to exercise. Researchers have engineered living muscle grafts that spontaneously contract beneath the skin and appear to reproduce some of exercise’s systemic effects, improving measures of muscle function, bone health and metabolism in aging mice [1]. The work, published […] The post Scientists create muscle that exercises itself appeared first on Longevity.Technology.

A new study published in Nature Aging reports that mice lacking the enzyme cGAS develop signs of premature aging, accompanied by the abnormal activation of repetitive genetic sequences known as LINE1 elements and a rise in inflammation. The findings place a cellular DNA-sensing pathway at the center of a biological connection between genome instability, transposable […]

Vulvovaginal candidiasis, a common fungal infection affecting women of reproductive age, may be facing a new kind of biological countermeasure. Researchers from institutions in Iran and Austria report that a cell-free preparation derived from bone marrow mesenchymal stem cells showed antifungal and antibiofilm activity against clinical Candida isolates, including strains classified as resistant to fluconazole, […]

Researchers developed a SuperLearner framework that combines established epigenetic clocks with machine learning to compare DNA methylation-based aging in residents of Costa Rica’s Nicoya Blue Zone with other Costa Ricans. Initial calibration suggested a modest younger epigenetic age among Nicoyans, but accounting more closely for age distribution substantially reduced the apparent advantage, highlighting the importance of population-specific calibration in longevity research.

Patients with sickle cell disease are often hesitant to undergo transformative gene therapy—the current lengthy process requires multiple hospital visits to collect enough stem cells. Researchers from Boston Children's Hospital have helped smooth the road to gene therapy with a new approach that collects enough of the patient's stem cells in a single hospital admission for most patients, improving the turnaround time for genetically altering and infusing the cells back into the patient. The long-term follow-up results of the first-in-human phase I pilot clinical trial were recently published in Blood.

In the years following type 2 diabetes diagnosis, women are more likely to develop mental health conditions, while men are more likely to develop cardiovascular and renal complications, according to a study published August 25th in the open access journal PLOS Medicine by Fabiola Eto from Queen Mary University of London, UK, and colleagues.

A dual stem cell scaffold improved vision and eye surface scores in a small first-in-human trial for aniridia-related keratopathy. For people with ARK (aniridia-related keratopathy), progressive damage to the eye’s surface can gradually cloud the cornea and severely reduce vision. In a first-in-human clinical trial at Moorfields Eye Hospital and University College London (UCL), a [...]

ALBANY — Grow NY Farms, a coalition of New York farmers, farmworkers, and agricultural organizations, today issued the following in response to a proposed rulemaking recently published by the New York State Public Employees Relations Board (PERB) governing procedures under the state’s farm labor law, which went into effect in 2020. “We appreciate PERB making progress to […] The post Grow NY Farms Responds to State’s Proposal About Farm Labor Organizing Procedures appeared first on Morning Ag Clips.

"Wildfire smoke should be treated as more than a temporary respiratory nuisance."

Icahn School of Medicine wins $1m award as its NYC-Vita trial pushes toward the finals of the world’s biggest healthy aging competition. Part of a ten-part series profiling each of the $101 million XPRIZE Healthspan competition’s Milestone 2 Awardees. Across the series, Longevity.Technology examines the science behind each team’s approach, the trial data supporting it […] The post Mount Sinai’s $1m XPRIZE bet: reset immune system, slow aging appeared first on Longevity.Technology.

Stem cells possess the unique ability to self-renew and transform into different types of cells. For example, rare hematopoietic stem cells found in bone marrow can become any type of blood cell. Throughout life, they can produce new blood cells to replace those lost because of infection, bleeding or chemotherapy.

In a new study, Mass General Brigham researchers explore the causes of immune aging, a barrier to successful cancer immunotherapy, and identify a gene that may serve as an age-related prognostic marker and potential target for future cancer therapies.

A new analysis of approximately 2.3 million people has examined whether following a Mediterranean-style diet is associated with a lower risk of pancreatic cancer, one of the most difficult cancers to detect and treat. Drawing on the Pooling Project of Prospective Studies of Diet and Cancer, the investigation brings together data from multiple large-scale studies […]

Epigenetic clocks can give ‘a vague concept of aging,’ but researchers are progressing to organ-specific techniques that provide actionable, medically meaningful data.

The slang term "touch grass" encourages people to step away from the internet or devices and connect with the real world. New research from the University of Kansas has found that a project that helps resettled refugees and immigrants learn sustainable farming has many of the term's same benefits, improving people's mental and physical well-being and training them to run independent agricultural businesses.

Diabetic foot ulcers are among the most stubborn complications of diabetes, combining poor circulation, persistent inflammation, microbial risk and a profound failure of tissue repair. A new study published in Military Medical Research describes a bioengineered strategy designed to address several of these problems at once. The researchers developed a treatment that combines trace-element-programmed exosomes […]

Mass General Brigham researchers have identified two genetic regulators that appear to drive the decline of cancer-fighting T cells in older bodies, offering a possible explanation for why cancer immunotherapies often work less effectively with age. In a study published in Cell, the team used large-scale CRISPR screening in aged, tumor-bearing mice to uncover molecular […]

A familiar cell-cycle protein may be helping aging cells broadcast inflammatory signals throughout the body, according to a new study published in Nature Aging. Researchers report that cyclin D1, or CCND1, and its partner enzyme CDK6 remain unusually active in senescent cells even after those cells have permanently stopped dividing. Rather than being a harmless […]

Researchers analyzing 51 longitudinal intervention studies found that reliable generation 2+ DNA methylation biomarkers, particularly those predicting mortality or pace of aging, were the most responsive to interventions aimed at longevity or healthspan. Pharmacological and lifestyle interventions produced the strongest biomarker changes, but the authors cautioned that responsiveness does not yet establish these measures as validated surrogate endpoints for slower aging or longer life.

Tropical forests may be able to return naturally across millions of square kilometres of degraded land, offering a powerful but unevenly distributed opportunity to fight climate change and slow biodiversity loss, according to a new global analysis. The study, published in Nature Ecology & Evolution, identifies where natural forest regeneration could deliver the greatest ecological […]

Alzheimer’s disease has long been described through the lens of neurons: the loss of synapses, the accumulation of amyloid-β plaques, and the formation of tau tangles. Yet the brain’s immune cells may determine whether this damage accelerates or is contained. A large-scale study published in Nature Genetics now offers one of the most detailed maps […]

Stem cells possess the unique ability to self-renew and transform into different types of cells. For example, rare hematopoietic stem cells found in bone marrow can become any type of blood cell.

AI-based tissue clocks reveal that human organs age on different timelines and that some of these patterns can be detected from blood. The age printed on a birth certificate tells only part of the story. Inside the body, the lungs, kidneys, pancreas, brain, and other organs may be aging along very different timelines, and artificial [...]

Sepsis can turn the immune system’s emergency response into a source of widespread tissue damage. When infection triggers an uncontrolled inflammatory cascade, the lungs are among the first organs to suffer. Blood vessels become leaky, immune cells accumulate in lung tissue, and the air sacs responsible for oxygen exchange can fill with fluid. This condition, […]

For decades, medicine has relied on a deceptively simple assumption: that many measurements in the blood remain relatively stable within each person. A cholesterol value, immune marker or liver enzyme can fluctuate from day to day, yet clinicians often interpret it against an individual’s broader biological baseline. A new 20-year study now suggests that this […]

Popular NAD+-boosting supplements like NMN and nicotinamide riboside may shield pancreatic cancer cells from chemotherapy, a new study warns.

Senescent cells accumulate with age throughout the body, either in response to forms of damage and stress or on reaching the Hayflick limit on replication. A senescent cell ceases to replicate, grows in size, and secretes a potent mix of pro-growth, pro-inflammatory signals. In youth, the immune system efficiently clears senescent cells, but with age this clearance falters. Like most of the progression of degenerative aging, the accumulation of senescent cells with age is nonlinear. This is in part because the decline of the immune system accelerates in later life, but it is also the case that the signaling generated by senescent cells can induce nearby cells to also become senescent. Thus senescent cells emerge at an accelerating pace as their numbers grow. In today's […]

The Lancet HIV Commission on Aging's 2026 report highlights how profoundly the global HIV epidemic is changing.

What we eat plays a vital role in maintaining a healthy lifestyle. A well-balanced meal rich in essential micronutrients not only fuels the body but may also help protect against metabolic and cardiovascular diseases. There is another question worth asking: Does when we eat matter just as much as what we eat?

Both too little and too much sleep may be linked to faster aging throughout the body. Researchers analyzing 23 biological aging clocks found the lowest aging levels among people sleeping about 6.4 to 7.8 hours per day. Short or long sleep was also associated with numerous conditions affecting the brain, heart, lungs, metabolism, and digestive system.

When Raghav Sehgal arrived at Yale as a graduate student several years ago, he wanted to explore the use of powerful computer science tools in cancer research. With an engineering background and a computational biology startup already under his belt, he was well prepared.

Maintenance therapy is linked to longer overall survival after first-line bevacizumab-based combination chemotherapy in patients with metastatic colorectal cancer, a study finds.

The various mitochondrial protein complexes are the building blocks of the electron transport chain, the complicated mechanism inside mitochondria that generates adenosine triphosphate (ATP), the chemical energy store molecule used to power cell activities. Nothing in a cell is simple, and the mitochondrial complexes do not operate neatly in isolation from one another. They drift in and out of supercomplex arrangements of multiple complexes, and it turns out that this supercomplex activity is important to mitochondrial function, and thus to the pace of aging. Researchers recently demonstrated that aging in mice can be slowed by inducing more supercomplex formation, for example. Here, find a review that covers what is known of the role of supercomplexes in aging and longevity. One of the hallmarks of aging […]

Ideas for individuals, workplaces, healthcare organizations and communities The post How to Celebrate September Is Healthy Aging® Month 2026 appeared first on Healthy Aging®.

Dogs and humans may share surprisingly similar metabolic signatures linked to lifespan. New research from the Dog Aging Project suggests that dogs and humans share some of the same biological patterns linked to lifespan. The finding could help scientists better understand how aging works in both species. In a study recently published in The Journals [...]

A smartwatch may be doing far more than counting steps. It may be quietly recording a shifting portrait of how the body ages—minute by minute, day after day. In a new study published in Nature Communications, researchers J. Shim and J. P. Onnela examine how commercial wearable devices can be used for the longitudinal digital […]